A true story by Geeta Anand
The remarkable true story of John Crowley’s race against time to found a business that would cure
his sick children. John and Aileen Crowley were on top of the world. With a brand-new Harvard
Business School degree, three beautiful children, a new house, and a great job, they thought that
they had just entered the best years of life. Then doctors diagnosed their two youngest children with
Pompe disease, and everything changed.
Fifteen-month-old Megan and five-month-old Patrick were given only months to live. Pompe disease,
the Crowleys were told, was so rare that no company had bothered spending the money needed to
sponsor research. There was no cure, no treatment—only the gradual degeneration of muscle so
that at the end, the children would be unable to walk, eat, or even breathe on their own. It was a
nightmare the Crowleys could hardly comprehend.
But John Crowley refused to accept this death sentence—and in the absence of other options, he
made his own. Determined to find scientists who could develop a replacement enzyme that would
keep the disease at bay and his children alive, Crowley quit his job as a financial consultant and
invested himself and his life savings in a biotechnology start-up company. In just over a year,
Novazyme Pharmaceuticals, Inc., went from an endowment of $37,000 to $27 million, and was sold to Genzyme Corp. soon
thereafter for a news-breaking $137.5 million. But the struggle wasn’t over yet, and scientific setbacks, accusations of conflict of
interest, business troubles, and the children’s own worsening condition would test the limits of John and Aileen’s minds and hearts as
they fought towards a cure.
With deft prose and devastating clarity, Pulitzer Prize-winning Wall Street Journal reporter Geeta Anand weaves together the
disparate threads of this remarkable story of cutting-edge science; of business acumen and daring; and of the indomitable fighting
spirit of a family that refuses to give in.
Heart-wrenching yet triumphant, The Cure takes readers from the boardrooms and laboratories to hospital beds and kindergarten
classrooms. With its captivating and ultimately deeply uplifting narrative, The Cure is a wholly American story of commerce and
technology, of determination and daring, and of family and the power of a belief in happy endings.
The book is available at www.thecurebook.com
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